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The Cellular Protein MCM3AP Is Required for Inhibition of Cellular DNA Synthesis by the IE86 Protein of Human Cytomegalovirus

Like all DNA viruses, human cytomegalovirus (HCMV) infection is known to result in profound effects on host cell cycle. Infection of fibroblasts with HCMV is known to induce an advance in cell cycle through the G(0)-G(1) phase and then a subsequent arrest of cell cycle in early S-phase, presumably r...

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Detalles Bibliográficos
Autores principales: Poole, Emma, Bain, Mark, Teague, Linda, Takei, Yoshinori, Laskey, Ron, Sinclair, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477159/
https://www.ncbi.nlm.nih.gov/pubmed/23094019
http://dx.doi.org/10.1371/journal.pone.0045686