Epithelial Mesenchymal Transition and Pancreatic Tumor Initiating CD44+/EpCAM+ Cells Are Inhibited by γ-Secretase Inhibitor IX

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a high rate of metastasis. Recent studies have indicated that the Notch signalling pathway is important in PDAC initiation and maintenance, although the specific cell biological roles of the pathway remain to be established. Here...

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Detalles Bibliográficos
Autores principales: Palagani, Vindhya, El Khatib, Mona, Kossatz, Uta, Bozko, Przemyslaw, Müller, Martin R., Manns, Michael P., Krech, Till, Malek, Nisar P., Plentz, Ruben R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477166/
https://www.ncbi.nlm.nih.gov/pubmed/23094026
http://dx.doi.org/10.1371/journal.pone.0046514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477166/
https://www.ncbi.nlm.nih.gov/pubmed/23094026
http://dx.doi.org/10.1371/journal.pone.0046514

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