Negative regulation of IL-17-mediated signaling and inflammation by ubiquitin-specific protease 25

Interleukin 17 (IL-17) plays an important role in infection and autoimmunity; how it signals remains poorly understood. In this study, we identified ubiquitin-specific protease 25 (USP25) as a negative regulator of IL-17-mediated signaling and inflammation. Overexpression of USP25 inhibited IL-17-tr...

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Detalles Bibliográficos
Autores principales: Zhong, Bo, Liu, Xikui, Wang, Xiaohu, Chang, Seon Hee, Liu, Xindong, Wang, Aibo, Reynolds, Joseph M., Dong, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477275/
https://www.ncbi.nlm.nih.gov/pubmed/23042150
http://dx.doi.org/10.1038/ni.2427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477275/
https://www.ncbi.nlm.nih.gov/pubmed/23042150
http://dx.doi.org/10.1038/ni.2427

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