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Negative regulation of IL-17-mediated signaling and inflammation by ubiquitin-specific protease 25

Interleukin 17 (IL-17) plays an important role in infection and autoimmunity; how it signals remains poorly understood. In this study, we identified ubiquitin-specific protease 25 (USP25) as a negative regulator of IL-17-mediated signaling and inflammation. Overexpression of USP25 inhibited IL-17-tr...

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Detalles Bibliográficos
Autores principales:	Zhong, Bo, Liu, Xikui, Wang, Xiaohu, Chang, Seon Hee, Liu, Xindong, Wang, Aibo, Reynolds, Joseph M., Dong, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477275/ https://www.ncbi.nlm.nih.gov/pubmed/23042150 http://dx.doi.org/10.1038/ni.2427

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