Embryonic expression of AMPK γ subunits and the identification of a novel γ2 transcript variant in adult heart

AMP-activated protein kinase (AMPK), the key sensor and regulator of cellular energy status, is a heterotrimeric enzyme with multiple isoforms for each subunit (α1/α 2; β1/β2; γ1/γ2/γ3). Mutations in PRKAG2, which encodes the γ2 regulatory subunit, cause a cardiomyopathy characterized by hypertrophy...

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Detalles Bibliográficos
Autores principales: Pinter, Katalin, Grignani, Robert T., Czibik, Gabor, Farza, Hend, Watkins, Hugh, Redwood, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477313/
https://www.ncbi.nlm.nih.gov/pubmed/22683324
http://dx.doi.org/10.1016/j.yjmcc.2012.05.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477313/
https://www.ncbi.nlm.nih.gov/pubmed/22683324
http://dx.doi.org/10.1016/j.yjmcc.2012.05.017

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