The Transcription Factors Egr2 and Egr3 Are Essential for the Control of Inflammation and Antigen-Induced Proliferation of B and T Cells

Lymphocytes provide optimal responses against pathogens with minimal inflammatory pathology. However, the intrinsic mechanisms regulating these responses are unknown. Here, we report that deletion of both transcription factors Egr2 and Egr3 in lymphocytes resulted in a lethal autoimmune syndrome wit...

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Detalles Bibliográficos
Autores principales: Li, Suling, Miao, Tizong, Sebastian, Meera, Bhullar, Punamdip, Ghaffari, Emma, Liu, Mengya, Symonds, Alistair L.J., Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477314/
https://www.ncbi.nlm.nih.gov/pubmed/23021953
http://dx.doi.org/10.1016/j.immuni.2012.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477314/
https://www.ncbi.nlm.nih.gov/pubmed/23021953
http://dx.doi.org/10.1016/j.immuni.2012.08.001

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