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Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

C-type lectin receptors (CLRs) that couple with the kinase Syk are major pattern recognition receptors for the activation of innate immunity and host defense. CLRs recognize fungi and other forms of microbial or sterile danger, and they induce inflammatory responses through the adaptor protein Card9...

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Detalles Bibliográficos
Autores principales: Strasser, Dominikus, Neumann, Konstantin, Bergmann, Hanna, Marakalala, Mohlopheni J., Guler, Reto, Rojowska, Anna, Hopfner, Karl-Peter, Brombacher, Frank, Urlaub, Henning, Baier, Gottfried, Brown, Gordon D., Leitges, Michael, Ruland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477316/
https://www.ncbi.nlm.nih.gov/pubmed/22265677
http://dx.doi.org/10.1016/j.immuni.2011.11.015