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Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity
C-type lectin receptors (CLRs) that couple with the kinase Syk are major pattern recognition receptors for the activation of innate immunity and host defense. CLRs recognize fungi and other forms of microbial or sterile danger, and they induce inflammatory responses through the adaptor protein Card9...
Autores principales: | Strasser, Dominikus, Neumann, Konstantin, Bergmann, Hanna, Marakalala, Mohlopheni J., Guler, Reto, Rojowska, Anna, Hopfner, Karl-Peter, Brombacher, Frank, Urlaub, Henning, Baier, Gottfried, Brown, Gordon D., Leitges, Michael, Ruland, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477316/ https://www.ncbi.nlm.nih.gov/pubmed/22265677 http://dx.doi.org/10.1016/j.immuni.2011.11.015 |
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