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Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro

Aluminium adjuvants (alum) have been the only widely approved adjuvants for use in human vaccines since the 1920s, however, the mechanism of action of these adjuvants remains elusive. Due to increasing demand for novel adjuvants, a clearer understanding of the mechanisms that allow these important a...

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Detalles Bibliográficos
Autores principales: Ghimire, Tirth R., Benson, Robert A., Garside, Paul, Brewer, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477319/
https://www.ncbi.nlm.nih.gov/pubmed/22732235
http://dx.doi.org/10.1016/j.imlet.2012.06.002