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Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro
Aluminium adjuvants (alum) have been the only widely approved adjuvants for use in human vaccines since the 1920s, however, the mechanism of action of these adjuvants remains elusive. Due to increasing demand for novel adjuvants, a clearer understanding of the mechanisms that allow these important a...
Autores principales: | Ghimire, Tirth R., Benson, Robert A., Garside, Paul, Brewer, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477319/ https://www.ncbi.nlm.nih.gov/pubmed/22732235 http://dx.doi.org/10.1016/j.imlet.2012.06.002 |
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