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Artesunate Exerts a Direct Effect on Endothelial Cell Activation and NF-κB Translocation in a Mechanism Independent of Plasmodium Killing

Artemisinin and its derivates are an important class of antimalarial drug and are described to possess immunomodulatory activities. Few studies have addressed the effect of artesunate in the murine malaria model or its effect on host immune response during malaria infection. Herein, we study the eff...

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Detalles Bibliográficos
Autores principales: Souza, Mariana C., Paixão, Flávio Henrique Marcolino, Ferraris, Fausto K., Ribeiro, Isabela, Henriques, Maria das Graças M. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477560/
https://www.ncbi.nlm.nih.gov/pubmed/23097741
http://dx.doi.org/10.1155/2012/679090