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Artesunate Exerts a Direct Effect on Endothelial Cell Activation and NF-κB Translocation in a Mechanism Independent of Plasmodium Killing
Artemisinin and its derivates are an important class of antimalarial drug and are described to possess immunomodulatory activities. Few studies have addressed the effect of artesunate in the murine malaria model or its effect on host immune response during malaria infection. Herein, we study the eff...
Autores principales: | Souza, Mariana C., Paixão, Flávio Henrique Marcolino, Ferraris, Fausto K., Ribeiro, Isabela, Henriques, Maria das Graças M. O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477560/ https://www.ncbi.nlm.nih.gov/pubmed/23097741 http://dx.doi.org/10.1155/2012/679090 |
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