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Release of Full-Length PrP(C) from Cultured Neurons Following Neurotoxic Challenge
The susceptibility of the normal cellular prion protein isoform, cellular prion protein (PrP(C)), to proteolytic digestion has been well documented. In addition, a link between PrP(C) and the cytosolic protease, calpain, has been reported although the specifics of the interaction remain unclear. We...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477638/ https://www.ncbi.nlm.nih.gov/pubmed/23093947 http://dx.doi.org/10.3389/fneur.2012.00147 |