Insights on Foxn1 Biological Significance and Usages of the “Nude” Mouse in Studies of T-Lymphopoiesis

Mutation in the “nude” gene, i.e. the FoxN1 gene, induces a hairless phenotype and a rudimentary thymus gland in mice (nude mouse) and humans (T-cell related primary immunodeficiency). Conventional FoxN1 gene knockout and transgenic mouse models have been generated for studies of FoxN1 gene function...

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Detalles Bibliográficos
Autores principales: Zhang, Zhijie, Burnley, Preston, Coder, Brandon, Su, Dong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477685/
https://www.ncbi.nlm.nih.gov/pubmed/23091413
http://dx.doi.org/10.7150/ijbs.5033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477685/
https://www.ncbi.nlm.nih.gov/pubmed/23091413
http://dx.doi.org/10.7150/ijbs.5033

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