New inhalation-optimized itraconazole nanoparticle-based dry powders for the treatment of invasive pulmonary aspergillosis

PURPOSE: Itraconazole (ITZ) dry powders for inhalation (DPI) composed of nanoparticles (NP) embedded in carrier microparticles were prepared and characterized. METHODS: DPIs were initially produced by reducing the ITZ particle size to the nanometer range using high-pressure homogenization with tocop...

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Detalles Bibliográficos
Autores principales: Duret, Christophe, Wauthoz, Nathalie, Sebti, Thami, Vanderbist, Francis, Amighi, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477927/
https://www.ncbi.nlm.nih.gov/pubmed/23093903
http://dx.doi.org/10.2147/IJN.S34091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477927/
https://www.ncbi.nlm.nih.gov/pubmed/23093903
http://dx.doi.org/10.2147/IJN.S34091

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