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New inhalation-optimized itraconazole nanoparticle-based dry powders for the treatment of invasive pulmonary aspergillosis

PURPOSE: Itraconazole (ITZ) dry powders for inhalation (DPI) composed of nanoparticles (NP) embedded in carrier microparticles were prepared and characterized. METHODS: DPIs were initially produced by reducing the ITZ particle size to the nanometer range using high-pressure homogenization with tocop...

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Detalles Bibliográficos
Autores principales:	Duret, Christophe, Wauthoz, Nathalie, Sebti, Thami, Vanderbist, Francis, Amighi, Karim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477927/ https://www.ncbi.nlm.nih.gov/pubmed/23093903 http://dx.doi.org/10.2147/IJN.S34091

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