High yield expression of catalytically active USP18 (UBP43) using a Trigger Factor fusion system

BACKGROUND: Covalent linkage of the ubiquitin-like protein ISG15 interferes with viral infection and USP18 is the major protease which specifically removes ISG15 from target proteins. Thus, boosting ISG15 modification by protease inhibition of USP18 might represent a new strategy to interfere with v...

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Detalles Bibliográficos
Autores principales: Basters, Anja, Ketscher, Lars, Deuerling, Elke, Arkona, Christoph, Rademann, Jörg, Knobeloch, Klaus-Peter, Fritz, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478164/
https://www.ncbi.nlm.nih.gov/pubmed/22916876
http://dx.doi.org/10.1186/1472-6750-12-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478164/
https://www.ncbi.nlm.nih.gov/pubmed/22916876
http://dx.doi.org/10.1186/1472-6750-12-56

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