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Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells

BACKGROUND: Recent data suggest that cancer stem cells (CSCs) play an important role in cancer, as these cells possess enhanced tumor-forming capabilities and are responsible for relapses after apparently curative therapies have been undertaken. Hence, novel cancer therapies will be needed to test f...

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Detalles Bibliográficos
Autores principales: Wang, Huiqiang, Chen, Nanhai G, Minev, Boris R, Szalay, Aladar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478222/
https://www.ncbi.nlm.nih.gov/pubmed/22901246
http://dx.doi.org/10.1186/1479-5876-10-167