Immune Modulation Mediated by Cryptococcal Laccase Promotes Pulmonary Growth and Brain Dissemination of Virulent Cryptococcus neoformans in Mice

C. neoformans is a leading cause of fatal mycosis linked to CNS dissemination. Laccase, encoded by the LAC1 gene, is an important virulence factor implicated in brain dissemination yet little is known about the mechanism(s) accounting for this observation. Here, we investigated whether the presence...

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Detalles Bibliográficos
Autores principales: Qiu, Yafeng, Davis, Michael J., Dayrit, Jeremy K., Hadd, Zachary, Meister, Daniel L., Osterholzer, John J., Williamson, Peter R., Olszewski, Michal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478276/
https://www.ncbi.nlm.nih.gov/pubmed/23110112
http://dx.doi.org/10.1371/journal.pone.0047853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478276/
https://www.ncbi.nlm.nih.gov/pubmed/23110112
http://dx.doi.org/10.1371/journal.pone.0047853

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