Chromosomal Instability in BRAF Mutant, Microsatellite Stable Colorectal Cancers

The BRAF oncogene is mutated in 15% of sporadic colorectal cancers. Approximately half of these BRAF mutant cancers demonstrate frequent frameshift mutations termed microsatellite instability (MSI), but are diploid and chromosomally stable. BRAF wild type cancers are typically microsatellite stable...

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Detalles Bibliográficos
Autores principales: Bond, Catherine E., Umapathy, Aarti, Buttenshaw, Ron L., Wockner, Leesa, Leggett, Barbara A., Whitehall, Vicki L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478278/
https://www.ncbi.nlm.nih.gov/pubmed/23110075
http://dx.doi.org/10.1371/journal.pone.0047483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478278/
https://www.ncbi.nlm.nih.gov/pubmed/23110075
http://dx.doi.org/10.1371/journal.pone.0047483

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