Interactions of pro-apoptotic BH3 proteins with anti-apoptotic Bcl-2 family proteins measured in live MCF-7 cells using FLIM FRET

Increased interactions between pro-apoptotic BH3-only proteins and anti-apoptotic Bcl-2 family proteins at mitochondria result in tumor initiation, progression and resistance to traditional chemotherapy. Drugs that mimic the BH3 region are expected to release BH3-only proteins from anti-apoptotic pr...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Leber, Brian, Andrews, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478303/
https://www.ncbi.nlm.nih.gov/pubmed/22895112
http://dx.doi.org/10.4161/cc.21462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478303/
https://www.ncbi.nlm.nih.gov/pubmed/22895112
http://dx.doi.org/10.4161/cc.21462

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