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Systemic shRNA mediated knock-down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation

The metastasis-inducing protein S100A4 was found to be a prognostic indicator for the development of metachronous metastases. S100A4 expression levels correlate with the formation of human colorectal cancer metastases and shorter patients’ survival. Inhibition of S100A4 expression in patients might...

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Detalles Bibliográficos
Autores principales: Dahlmann, Mathias, Sack, Ulrike, Herrmann, Pia, Lemm, Margit, Fichtner, Iduna, Schlag, Peter M., Stein, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478456/
https://www.ncbi.nlm.nih.gov/pubmed/22878175