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Systemic shRNA mediated knock-down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation
The metastasis-inducing protein S100A4 was found to be a prognostic indicator for the development of metachronous metastases. S100A4 expression levels correlate with the formation of human colorectal cancer metastases and shorter patients’ survival. Inhibition of S100A4 expression in patients might...
Autores principales: | Dahlmann, Mathias, Sack, Ulrike, Herrmann, Pia, Lemm, Margit, Fichtner, Iduna, Schlag, Peter M., Stein, Ulrike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478456/ https://www.ncbi.nlm.nih.gov/pubmed/22878175 |
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