Cargando…

Constitutive and Inflammatory Immunopeptidome of Pancreatic β-Cells

Type 1 diabetes is characterized by the autoimmune destruction of pancreatic β-cells. Recognition of major histocompatibility complex (MHC)-bound peptides is critical for both the initiation and progression of disease. In this study, MHC peptide complexes were purified from NIT-1 β-cells, interferon...

Descripción completa

Detalles Bibliográficos
Autores principales: Dudek, Nadine L., Tan, Chor Teck, Gorasia, Dhana G., Croft, Nathan P., Illing, Patricia T., Purcell, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478525/
https://www.ncbi.nlm.nih.gov/pubmed/22872234
http://dx.doi.org/10.2337/db11-1333