Therapeutic Potential of a Monoclonal Antibody Blocking the Wnt Pathway in Diabetic Retinopathy

Dysregulation of Wnt/β-catenin signaling contributes to the development of diabetic retinopathy by inducing retinal inflammation, vascular leakage, and neovascularization. Here, we evaluated the inhibitory effect of a monoclonal antibody (Mab) specific for the E1E2 domain of Wnt coreceptor low-densi...

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Detalles Bibliográficos
Autores principales: Lee, Kyungwon, Hu, Yang, Ding, Lexi, Chen, Ying, Takahashi, Yusuke, Mott, Robert, Ma, Jian-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478529/
https://www.ncbi.nlm.nih.gov/pubmed/22891217
http://dx.doi.org/10.2337/db11-0300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478529/
https://www.ncbi.nlm.nih.gov/pubmed/22891217
http://dx.doi.org/10.2337/db11-0300

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