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Cytotoxic Mechanisms Employed by Mouse T Cells to Destroy Pancreatic β-Cells
Several cytotoxic mechanisms have been attributed to T cells participating in β-cell death in type 1 diabetes. However, sensitivity of β-cells to these mechanisms in vitro and in vivo is likely to be different. Moreover, CD4(+) and CD8(+) T cells may use distinct mechanisms to cause β-cell demise th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Diabetes Association
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478530/ https://www.ncbi.nlm.nih.gov/pubmed/22773667 http://dx.doi.org/10.2337/db11-1784 |