Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

Aging is closely associated with muscle insulin resistance, hyperlipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes. We examined the hypothesis that muscle insulin resistance in healthy aging promotes increased hepatic de novo lipogenesis (DNL) and hyperlipidemia by altering th...

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Detalles Bibliográficos
Autores principales: Flannery, Clare, Dufour, Sylvie, Rabøl, Rasmus, Shulman, Gerald I., Petersen, Kitt Falk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478531/
https://www.ncbi.nlm.nih.gov/pubmed/22829450
http://dx.doi.org/10.2337/db12-0206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478531/
https://www.ncbi.nlm.nih.gov/pubmed/22829450
http://dx.doi.org/10.2337/db12-0206

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