Adipose Tissue TCF7L2 Splicing Is Regulated by Weight Loss and Associates With Glucose and Fatty Acid Metabolism

We investigated the effects of obesity surgery-induced weight loss on transcription factor 7-like 2 gene (TCF7L2) alternative splicing in adipose tissue and liver. Furthermore, we determined the association of TCF7L2 splicing with the levels of plasma glucose and serum free fatty acids (FFAs) in thr...

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Detalles Bibliográficos
Autores principales: Kaminska, Dorota, Kuulasmaa, Tiina, Venesmaa, Sari, Käkelä, Pirjo, Vaittinen, Maija, Pulkkinen, Leena, Pääkkönen, Matti, Gylling, Helena, Laakso, Markku, Pihlajamäki, Jussi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478533/
https://www.ncbi.nlm.nih.gov/pubmed/23086040
http://dx.doi.org/10.2337/db12-0239