NADPH Oxidase NOX2 Defines a New Antagonistic Role for Reactive Oxygen Species and cAMP/PKA in the Regulation of Insulin Secretion

In insulin-secreting cells, expression of NADPH oxidase (NOX), a potent source of ROS, has been reported, along with controversial findings regarding its function. Here, the role of NOXs was investigated: first by expression and cellular localization in mouse and human pancreatic islets, and then by...

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Detalles Bibliográficos
Autores principales: Li, Ning, Li, Bin, Brun, Thierry, Deffert-Delbouille, Christine, Mahiout, Zahia, Daali, Youssef, Ma, Xiao-Juan, Krause, Karl-Heinz, Maechler, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478534/
https://www.ncbi.nlm.nih.gov/pubmed/22933115
http://dx.doi.org/10.2337/db12-0009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478534/
https://www.ncbi.nlm.nih.gov/pubmed/22933115
http://dx.doi.org/10.2337/db12-0009

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