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B-Cell Cross-Presentation of Autologous Antigen Precipitates Diabetes
For autoimmune conditions like type 1 diabetes to progress, self-reactive CD8(+) T cells would need to interact with peptide–antigen cross-presented on the surface of antigen-presenting cells in a major histocompatibility complex (MHC) class I-restricted fashion. However, the mechanisms by which aut...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Diabetes Association
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478535/ https://www.ncbi.nlm.nih.gov/pubmed/22829452 http://dx.doi.org/10.2337/db12-0006 |