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B-Cell Cross-Presentation of Autologous Antigen Precipitates Diabetes

For autoimmune conditions like type 1 diabetes to progress, self-reactive CD8(+) T cells would need to interact with peptide–antigen cross-presented on the surface of antigen-presenting cells in a major histocompatibility complex (MHC) class I-restricted fashion. However, the mechanisms by which aut...

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Detalles Bibliográficos
Autores principales:	Mariño, Eliana, Tan, Bernice, Binge, Lauren, Mackay, Charles R., Grey, Shane T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478535/ https://www.ncbi.nlm.nih.gov/pubmed/22829452 http://dx.doi.org/10.2337/db12-0006

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