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Caloric Restriction Chronically Impairs Metabolic Programming in Mice

Although obesity rates are rapidly rising, caloric restriction remains one of the few safe therapies. Here we tested the hypothesis that obesity-associated disorders are caused by increased adipose tissue as opposed to excess dietary lipids. Fat mass (FM) of lean C57B6 mice fed a high-fat diet (HFD;...

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Detalles Bibliográficos
Autores principales: Kirchner, Henriette, Hofmann, Susanna M., Fischer-Rosinský, Antje, Hembree, Jazzminn, Abplanalp, William, Ottaway, Nickki, Donelan, Elizabeth, Krishna, Radha, Woods, Stephen C., Müller, Timo D., Spranger, Joachim, Perez-Tilve, Diego, Pfluger, Paul T., Tschöp, Matthias H., Habegger, Kirk M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478536/
https://www.ncbi.nlm.nih.gov/pubmed/22787140
http://dx.doi.org/10.2337/db11-1621