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Caloric Restriction Chronically Impairs Metabolic Programming in Mice
Although obesity rates are rapidly rising, caloric restriction remains one of the few safe therapies. Here we tested the hypothesis that obesity-associated disorders are caused by increased adipose tissue as opposed to excess dietary lipids. Fat mass (FM) of lean C57B6 mice fed a high-fat diet (HFD;...
Autores principales: | Kirchner, Henriette, Hofmann, Susanna M., Fischer-Rosinský, Antje, Hembree, Jazzminn, Abplanalp, William, Ottaway, Nickki, Donelan, Elizabeth, Krishna, Radha, Woods, Stephen C., Müller, Timo D., Spranger, Joachim, Perez-Tilve, Diego, Pfluger, Paul T., Tschöp, Matthias H., Habegger, Kirk M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478536/ https://www.ncbi.nlm.nih.gov/pubmed/22787140 http://dx.doi.org/10.2337/db11-1621 |
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