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Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance

The antidiabetic and antiatherosclerotic effects of adiponectin make it a desirable drug target for the treatment of metabolic and cardiovascular diseases. However, the adiponectin-based drug development approach turns out to be difficult due to extremely high serum levels of this adipokine. On the...

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Detalles Bibliográficos
Autores principales: Liu, Meilian, Xiang, Ruihua, Wilk, Sarah Ann, Zhang, Ning, Sloane, Lauren B., Azarnoush, Kian, Zhou, Lijun, Chen, Hongzhi, Xiang, Guangda, Walter, Christi A., Austad, Steven N., Musi, Nicolas, DeFronzo, Ralph A., Asmis, Reto, Scherer, Philipp E., Dong, Lily Q., Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478538/
https://www.ncbi.nlm.nih.gov/pubmed/22807031
http://dx.doi.org/10.2337/db12-0169