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Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance
The antidiabetic and antiatherosclerotic effects of adiponectin make it a desirable drug target for the treatment of metabolic and cardiovascular diseases. However, the adiponectin-based drug development approach turns out to be difficult due to extremely high serum levels of this adipokine. On the...
Autores principales: | Liu, Meilian, Xiang, Ruihua, Wilk, Sarah Ann, Zhang, Ning, Sloane, Lauren B., Azarnoush, Kian, Zhou, Lijun, Chen, Hongzhi, Xiang, Guangda, Walter, Christi A., Austad, Steven N., Musi, Nicolas, DeFronzo, Ralph A., Asmis, Reto, Scherer, Philipp E., Dong, Lily Q., Liu, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478538/ https://www.ncbi.nlm.nih.gov/pubmed/22807031 http://dx.doi.org/10.2337/db12-0169 |
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