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Genetic Dissection of Complex Genetic Factor Involved in NIDDM of OLETF Rat

The Otsuka Long-Evans Tokushima Fatty (OLETF) rat is an animal model for obese-type, noninsulin-dependent diabetes mellitus (NIDDM) in humans. NIDDM in this rat model was shown to be regulated by multiple genes. We have identified 14 quantitative trait loci (QTLs) responsible for NIDDM (Nidd1-14/of)...

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Detalles Bibliográficos
Autores principales: Yamada, Takahisa, Kose, Hiroyuki, Ohta, Takeshi, Matsumoto, Kozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478749/
https://www.ncbi.nlm.nih.gov/pubmed/23118743
http://dx.doi.org/10.1155/2012/582546