Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma

Kaposi’s sarcoma (KS), a multifocal vascular neoplasm linked to human herpesvirus-8 (HHV-8/KS-associated herpesvirus [KSHV]) infection, is the most common AIDS-associated malignancy. Clinical management of KS has proven to be challenging because of its prevalence in immunosuppressed patients and its...

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Detalles Bibliográficos
Autores principales: Croci, Diego O., Salatino, Mariana, Rubinstein, Natalia, Cerliani, Juan P., Cavallin, Lucas E., Leung, Howard J., Ouyang, Jing, Ilarregui, Juan M., Toscano, Marta A., Domaica, Carolina I., Croci, María C., Shipp, Margaret A., Mesri, Enrique A., Albini, Adriana, Rabinovich, Gabriel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478924/
https://www.ncbi.nlm.nih.gov/pubmed/23027923
http://dx.doi.org/10.1084/jem.20111665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478924/
https://www.ncbi.nlm.nih.gov/pubmed/23027923
http://dx.doi.org/10.1084/jem.20111665

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