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Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma
Kaposi’s sarcoma (KS), a multifocal vascular neoplasm linked to human herpesvirus-8 (HHV-8/KS-associated herpesvirus [KSHV]) infection, is the most common AIDS-associated malignancy. Clinical management of KS has proven to be challenging because of its prevalence in immunosuppressed patients and its...
Autores principales: | Croci, Diego O., Salatino, Mariana, Rubinstein, Natalia, Cerliani, Juan P., Cavallin, Lucas E., Leung, Howard J., Ouyang, Jing, Ilarregui, Juan M., Toscano, Marta A., Domaica, Carolina I., Croci, María C., Shipp, Margaret A., Mesri, Enrique A., Albini, Adriana, Rabinovich, Gabriel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478924/ https://www.ncbi.nlm.nih.gov/pubmed/23027923 http://dx.doi.org/10.1084/jem.20111665 |
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