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TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice

Apoptotic death of alveolar macrophages observed during lung infection with Streptococcus pneumoniae is thought to limit overwhelming lung inflammation in response to bacterial challenge. However, the underlying apoptotic death mechanism has not been defined. Here, we examined the role of the TNF su...

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Detalles Bibliográficos
Autores principales: Steinwede, Kathrin, Henken, Stefanie, Bohling, Jennifer, Maus, Regina, Ueberberg, Bianca, Brumshagen, Christina, Brincks, Erik L., Griffith, Thomas S., Welte, Tobias, Maus, Ulrich A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478925/
https://www.ncbi.nlm.nih.gov/pubmed/23071253
http://dx.doi.org/10.1084/jem.20120983