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TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice
Apoptotic death of alveolar macrophages observed during lung infection with Streptococcus pneumoniae is thought to limit overwhelming lung inflammation in response to bacterial challenge. However, the underlying apoptotic death mechanism has not been defined. Here, we examined the role of the TNF su...
Autores principales: | Steinwede, Kathrin, Henken, Stefanie, Bohling, Jennifer, Maus, Regina, Ueberberg, Bianca, Brumshagen, Christina, Brincks, Erik L., Griffith, Thomas S., Welte, Tobias, Maus, Ulrich A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478925/ https://www.ncbi.nlm.nih.gov/pubmed/23071253 http://dx.doi.org/10.1084/jem.20120983 |
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