TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation

Lung vascular endothelial barrier disruption and the accompanying inflammation are primary pathogenic features of acute lung injury (ALI); however, the basis for the development of both remains unclear. Studies have shown that activation of transient receptor potential canonical (TRPC) channels indu...

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Detalles Bibliográficos
Autores principales: Tauseef, Mohammad, Knezevic, Nebojsa, Chava, Koteswara R., Smith, Monica, Sukriti, Sukriti, Gianaris, Nicholas, Obukhov, Alexander G., Vogel, Stephen M., Schraufnagel, Dean E., Dietrich, Alexander, Birnbaumer, Lutz, Malik, Asrar B., Mehta, Dolly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478927/
https://www.ncbi.nlm.nih.gov/pubmed/23045603
http://dx.doi.org/10.1084/jem.20111355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478927/
https://www.ncbi.nlm.nih.gov/pubmed/23045603
http://dx.doi.org/10.1084/jem.20111355

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