Induction of tumoricidal function in CD4(+) T cells is associated with concomitant memory and terminally differentiated phenotype

Harnessing the adaptive immune response to treat malignancy is now a clinical reality. Several strategies are used to treat melanoma; however, very few result in a complete response. CD4(+) T cells are important and potent mediators of anti-tumor immunity and adoptive transfer of specific CD4(+) T c...

Descripción completa

Detalles Bibliográficos
Autores principales: Hirschhorn-Cymerman, Daniel, Budhu, Sadna, Kitano, Shigehisa, Liu, Cailian, Zhao, Feng, Zhong, Hong, Lesokhin, Alexander M., Avogadri-Connors, Francesca, Yuan, Jianda, Li, Yanyun, Houghton, Alan N., Merghoub, Taha, Wolchok, Jedd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478933/
https://www.ncbi.nlm.nih.gov/pubmed/23008334
http://dx.doi.org/10.1084/jem.20120532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478933/
https://www.ncbi.nlm.nih.gov/pubmed/23008334
http://dx.doi.org/10.1084/jem.20120532

Ejemplares similares