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Tryptophan hydroxylase-1 regulates immune tolerance and inflammation
Nutrient deprivation based on the loss of essential amino acids by catabolic enzymes in the microenvironment is a critical means to control inflammatory responses and immune tolerance. Here we report the novel finding that Tph-1 (tryptophan hydroxylase-1), a synthase which catalyses the conversion o...
Autores principales: | Nowak, Elizabeth C., de Vries, Victor C., Wasiuk, Anna, Ahonen, Cory, Bennett, Kathryn A., Le Mercier, Isabelle, Ha, Dae-Gon, Noelle, Randolph J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478935/ https://www.ncbi.nlm.nih.gov/pubmed/23008335 http://dx.doi.org/10.1084/jem.20120408 |
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