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Cell surface sialylation affects binding of enterovirus 71 to rhabdomyosarcoma and neuroblastoma cells

BACKGROUND: Enterovirus 71 (EV71) is a major causative agent of hand-foot-and-mouth disease (HFMD), and infection of EV71 to central nerve system (CNS) may result in a high mortality in children less than 2 years old. Although there are two highly glycosylated membrane proteins, SCARB2 and PSGL-1, w...

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Detalles Bibliográficos
Autores principales: Su, Pei-Yi, Liu, Yueh-Tung, Chang, Hsin-Yueh, Huang, Sheng-Wen, Wang, Ya-Fang, Yu, Chun-Keung, Wang, Jen-Ren, Chang, Chuan-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478995/
https://www.ncbi.nlm.nih.gov/pubmed/22853823
http://dx.doi.org/10.1186/1471-2180-12-162