Cargando…

Characterization of CDKN2A(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing

BACKGROUND: The aim of this study is to analyse CDKN2A methylation using pyrosequencing on a large cohort of colorectal cancers and corresponding non-neoplastic tissues. In a second step, the effect of methylation on clinical outcome is addressed. METHODS: Primary colorectal cancers and matched non-...

Descripción completa

Detalles Bibliográficos
Autores principales: Bihl, Michel P, Foerster, Anja, Lugli, Alessandro, Zlobec, Inti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479016/
https://www.ncbi.nlm.nih.gov/pubmed/22925370
http://dx.doi.org/10.1186/1479-5876-10-173