Neutral lipids associated with haemozoin mediate efficient and rapid β-haematin formation at physiological pH, temperature and ionic composition

BACKGROUND: The malaria parasite disposes of host-derived ferrihaem (iron(III)protoporphyrin IX, Fe(III)PPIX) by conversion to crystalline haemozoin in close association with neutral lipids. Lipids mediate synthetic haemozoin (β-haematin) formation very efficiently. However, the effect on reaction r...

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Detalles Bibliográficos
Autores principales: Ambele, Melvin A, Egan, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479076/
https://www.ncbi.nlm.nih.gov/pubmed/23043460
http://dx.doi.org/10.1186/1475-2875-11-337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479076/
https://www.ncbi.nlm.nih.gov/pubmed/23043460
http://dx.doi.org/10.1186/1475-2875-11-337

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