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Catechol-O-Methyltransferase val158met Polymorphism Predicts Placebo Effect in Irritable Bowel Syndrome

Identifying patients who are potential placebo responders has major implications for clinical practice and trial design. Catechol-O-methyltransferase (COMT), an important enzyme in dopamine catabolism plays a key role in processes associated with the placebo effect such as reward, pain, memory and l...

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Detalles Bibliográficos
Autores principales: Hall, Kathryn T., Lembo, Anthony J., Kirsch, Irving, Ziogas, Dimitrios C., Douaiher, Jeffrey, Jensen, Karin B., Conboy, Lisa A., Kelley, John M., Kokkotou, Efi, Kaptchuk, Ted J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479140/
https://www.ncbi.nlm.nih.gov/pubmed/23110189
http://dx.doi.org/10.1371/journal.pone.0048135