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Catechol-O-Methyltransferase val158met Polymorphism Predicts Placebo Effect in Irritable Bowel Syndrome
Identifying patients who are potential placebo responders has major implications for clinical practice and trial design. Catechol-O-methyltransferase (COMT), an important enzyme in dopamine catabolism plays a key role in processes associated with the placebo effect such as reward, pain, memory and l...
Autores principales: | Hall, Kathryn T., Lembo, Anthony J., Kirsch, Irving, Ziogas, Dimitrios C., Douaiher, Jeffrey, Jensen, Karin B., Conboy, Lisa A., Kelley, John M., Kokkotou, Efi, Kaptchuk, Ted J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479140/ https://www.ncbi.nlm.nih.gov/pubmed/23110189 http://dx.doi.org/10.1371/journal.pone.0048135 |
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