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A Large Extension to HIV-1 Gag, Like Pol, Has Negative Impacts on Virion Assembly

The GagPol protein of HIV-1 harbors viral enzymes, such as protease (PR), reverse transcriptase, and integrase, that are all crucial for virion infectivity. Previous studies have suggested that expression of GagPol alone does not produce viral particles and that the budding defect is caused by the p...

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Detalles Bibliográficos
Autores principales: Haraguchi, Hiyori, Noda, Takeshi, Kawaoka, Yoshihiro, Morikawa, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479142/
https://www.ncbi.nlm.nih.gov/pubmed/23110110
http://dx.doi.org/10.1371/journal.pone.0047828