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A Large Extension to HIV-1 Gag, Like Pol, Has Negative Impacts on Virion Assembly
The GagPol protein of HIV-1 harbors viral enzymes, such as protease (PR), reverse transcriptase, and integrase, that are all crucial for virion infectivity. Previous studies have suggested that expression of GagPol alone does not produce viral particles and that the budding defect is caused by the p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479142/ https://www.ncbi.nlm.nih.gov/pubmed/23110110 http://dx.doi.org/10.1371/journal.pone.0047828 |